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The impact of antibodies on clinical outcomes in diseases treated with therapeutic protein: Lessons learned from infantile Pompe disease

PURPOSE: Enzyme replacement therapy with rhGAA (Myozyme(®)) has lead to improved survival, which is largely attributable to improvements in cardiomyopathy and skeletal muscle function. However, crossreactive immunologic material-negative patients have a poor clinical response to enzyme replacement t...

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Bibliografische gegevens
Hoofdauteurs: Banugaria, Suhrad G., Prater, Sean N., Ng, Yiu-Ki, Kobori, Joyce A., Finkel, Richard S., Ladda, Roger L., Chen, Yuan-Tsong, Rosenberg, Amy S., Kishnani, Priya S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954622/
https://ncbi.nlm.nih.gov/pubmed/21637107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GIM.0b013e3182174703
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