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Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria.

ATP dependent proteolytic degradation of misfolded proteins in the mitochondrial matrix is mediated by the PIM1 protease and depends on the molecular chaperone proteins mt-hsp70 and Mdj1p. Chaperone function is essential to maintain misfolded proteins in a soluble state, a prerequisite for their deg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wagner, I, Arlt, H, van Dyck, L, Langer, T, Neupert, W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC395461/
https://ncbi.nlm.nih.gov/pubmed/7957078
Etiketak: Etiketa erantsi
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