Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

Clostridial neurotoxins inhibit neurotransmitter release by selective and specific intracellular proteolysis of synaptobrevin/VAMP, synaptosomal-associated protein of 25 kDa (SNAP-25) or syntaxin. Here we show that in binary reactions synaptobrevin binds weakly to both SNAP-25 and syntaxin, and SNAP...

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Bibliographic Details
Main Authors: Hayashi, T, McMahon, H, Yamasaki, S, Binz, T, Hata, Y, Südhof, T C, Niemann, H
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395451/
https://ncbi.nlm.nih.gov/pubmed/7957071
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