Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.

A 20S complex composed of the cytosolic fusion proteins NSF and SNAP and the synaptosomal SNAP receptors (SNAREs) synaptobrevin, syntaxin and SNAP-25 is essential for synaptic vesicle exocytosis. Formation of this complex is thought to be regulated by synaptotagmin, the putative calcium sensor of ne...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Pellegrini, L L, O'Connor, V, Lottspeich, F, Betz, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7588600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00152.x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!