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Antihyperalgesic effects of imidazoline I(2) receptor ligands in rat models of inflammatory and neuropathic pain

BACKGROUND AND PURPOSE: A new imidazoline I(2) receptor ligand, CR4056, is effective for chronic inflammatory pain and diabetic neuropathy. However, it is unclear whether other I(2) receptor ligands have similar effects and whether antinociceptive tolerance develops with repeated treatment. EXPERIME...

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Detalhes bibliográficos
Main Authors: Li, Jun-Xu, Thorn, David A, Qiu, Yanyan, Peng, Bi-Wen, Zhang, Yanan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954494/
https://ncbi.nlm.nih.gov/pubmed/24329196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12555
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