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PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells

BACKGROUND AND PURPOSE: A major challenge in the development of new medicines targeting GPCRs is the ability to quantify drug action in physiologically relevant models. Primary cell models that closely resemble the clinically relevant in vivo site of drug action are important translational tools in...

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Bibliografiske detaljer
Main Authors: Walker, C S, Sundrum, T, Hay, D L
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954490/
https://ncbi.nlm.nih.gov/pubmed/24303997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12541
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