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LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels

Background and PurposeRetinoids, through their activation of retinoic acid receptors (RARs) and retinoid X receptors, regulate diverse cellular processes, and pharmacological intervention in their actions has been successful in the treatment of skin disorders and cancers. Despite the many beneficial...

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Bibliographic Details
Main Authors: Yin, Shijin, Luo, Jialie, Qian, Aihua, Yu, Weihua, Hu, Hongzhen
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954489/
https://ncbi.nlm.nih.gov/pubmed/24308840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12543
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