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Sensory TRP channels contribute differentially to skin inflammation and persistent itch
Although both persistent itch and inflammation are commonly associated with allergic contact dermatitis (ACD), it is not known if they are mediated by shared or distinct signaling pathways. Here we show that both TRPA1 and TRPV1 channels are required for generating spontaneous scratching in a mouse...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661746/ https://ncbi.nlm.nih.gov/pubmed/29081531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01056-8 |
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