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Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel.

Phospholamban is a 52 amino acid calcium regulatory protein found as pentamers in cardiac SR membranes. The pentamers form through interactions between its transmembrane domains, and are stable in SDS. We have employed a saturation mutagenesis approach to study the detailed interactions between the...

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Detalhes bibliográficos
Main Authors: Arkin, I T, Adams, P D, MacKenzie, K R, Lemmon, M A, Brünger, A T, Engelman, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395414/
https://ncbi.nlm.nih.gov/pubmed/7525269
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