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Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

We have characterized the mechanism by which the subcellular distribution of c-Src is controlled by the phosphorylation of tyrosine 527. Mutation of this tyrosine dramatically redistributes c-Src from endosomal membranes to focal adhesions. Redistribution to focal adhesions occurs independently of k...

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Bibliografiske detaljer
Main Authors: Kaplan, K B, Bibbins, K B, Swedlow, J R, Arnaud, M, Morgan, D O, Varmus, H E
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395413/
https://ncbi.nlm.nih.gov/pubmed/7525268
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