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WD40-repeat proteins control the flow of Gβγ signaling for directional cell migration

The ability of cells to generate a highly polarized intracellular signal through G protein-coupled receptors (GPCRs) is essential for their migration toward chemoattractants. The Gβγ subunits of heterotrimeric G proteins play a critical role in transmitting chemotactic signals from GPCRs via the act...

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Библиографические подробности
Главные авторы: Runne, Caitlin, Chen, Songhai
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954032/
https://ncbi.nlm.nih.gov/pubmed/23302952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.22940
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