Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901

BACKGROUND: Quinacrine (QC), an antimalarial drug, has been shown to possess anticancer effect both in vitro (cancer cell lines) and in vivo (mouse models). In the cancer cells, QC can simultaneously suppress nuclear factor-κB and activate p53 signaling, which results in the induction of the apoptos...

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Autors principals: Wu, Xiaoyang, Wang, Yunliang, Wang, Hongwei, Wang, Qiang, Wang, Lin, Miao, Jingcheng, Cui, Fengmei, Wang, Jinzhi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2012
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954015/
https://ncbi.nlm.nih.gov/pubmed/24653512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2012.02.003
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