Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901

BACKGROUND: Quinacrine (QC), an antimalarial drug, has been shown to possess anticancer effect both in vitro (cancer cell lines) and in vivo (mouse models). In the cancer cells, QC can simultaneously suppress nuclear factor-κB and activate p53 signaling, which results in the induction of the apoptos...

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Detalhes bibliográficos
Main Authors: Wu, Xiaoyang, Wang, Yunliang, Wang, Hongwei, Wang, Qiang, Wang, Lin, Miao, Jingcheng, Cui, Fengmei, Wang, Jinzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954015/
https://ncbi.nlm.nih.gov/pubmed/24653512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2012.02.003
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