Snail as a Potential Target Molecule in Cardiac Fibrosis: Paracrine Action of Endothelial Cells on Fibroblasts Through Snail and CTGF Axis

Ischemia/reperfusion (I/R) injury to myocardium induces death of cardiomyocytes and destroys the vasculature, leading to cardiac fibrosis that is mainly mediated by the transdifferentiation of fibroblasts to myofibroblasts and the collagen deposition. Snail involvement in fibrosis is well known; how...

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Main Authors: Lee, Sae-Won, Won, Joo-Yun, Kim, Woo Jean, Lee, Jaewon, Kim, Kyung-Hee, Youn, Seock-Won, Kim, Ju-Young, Lee, Eun Ju, Kim, Yong-Jin, Kim, Kyu-Won, Kim, Hyo-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953993/
https://ncbi.nlm.nih.gov/pubmed/23760445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.146
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