Anti-epidermal growth factor receptor monoclonal antibody-based therapy for metastatic colorectal cancer: a meta-analysis of the effect of PIK3CA mutations in KRAS wild-type patients

INTRODUCTION: We conducted a meta-analysis to dissect the association between PIK3CA mutations (exon 9 and exon 20) and resistance to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (MoAbs) in KRAS wild-type metastatic colorectal cancer (mCRC) patients. MATERIAL AND METHODS: In 11...

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Библиографические подробности
Главные авторы: Huang, Lulu, Liu, Zhenfang, Deng, Donghong, Tan, Aihua, Liao, Ming, Mo, Zengnan, Yang, Xiaobo
Формат: Artigo
Язык:Inglês
Опубликовано: Termedia Publishing House 2014
Предметы:
Systematic review/Meta-analysis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953972/
https://ncbi.nlm.nih.gov/pubmed/24701207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2014.40728
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