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Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene.

v-cbl is the transforming gene of a murine retrovirus which induces pre-B cell lymphomas and myelogenous leukaemias. It encodes 40 kDa of a gag fusion protein which is localized in the cytoplasm and nucleus of infected cells. The c-cbl oncogene encodes a 120 kDa cytoplasmic protein and its overexpre...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Andoniou, C E, Thien, C B, Langdon, W Y
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7925293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06773.x
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