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Role of coreceptors in positive selection and lineage commitment.

Recent experiments have re-awakened interest in a stochastic/selective model of positive selection of T lymphocytes. A revised version of the model has been proposed whereby commitment of double-positive thymocytes to either the CD4 or CD8 lineage requires two engagements with MHC molecules: the fir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Chan, S H, Waltzinger, C, Baron, A, Benoist, C, Mathis, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7925290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06770.x
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