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A New Strategy to Rapidly Evaluate Kinetics of Glucuronide Efflux by Breast Cancer Resistance Protein (BCRP/ABCG2)

PURPOSE: The efflux transporter breast cancer resistance protein (BCRP/ABCG2) plays an important role in excretion of anionic drugs and metabolites including glucuronides in humans. METHODS: In this article, our recently published cell model (i.e., HeLa cells over-expressing UGT1A9 (HeLa1A9)) is use...

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Bibliografiske detaljer
Main Authors: Wu, Baojian, Jiang, Wen, Yin, Taijun, Gao, Song, Hu, Ming
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953450/
https://ncbi.nlm.nih.gov/pubmed/22752253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0817-2
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