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Adaptive Gene Amplification As an Intermediate Step in the Expansion of Virus Host Range

The majority of recently emerging infectious diseases in humans is due to cross-species pathogen transmissions from animals. To establish a productive infection in new host species, viruses must overcome barriers to replication mediated by diverse and rapidly evolving host restriction factors such a...

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Detalhes bibliográficos
Main Authors: Brennan, Greg, Kitzman, Jacob O., Rothenburg, Stefan, Shendure, Jay, Geballe, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953438/
https://ncbi.nlm.nih.gov/pubmed/24626510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004002
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