Specific Contactin N-Glycans Are Implicated in Neurofascin Binding and Autoimmune Targeting in Peripheral Neuropathies

Cell adhesion molecules (CAMs) play a crucial role in the formation of the nodes of Ranvier and in the rapid propagation of the nerve impulses along myelinated axons. These CAMs are the targets of autoimmunity in inflammatory neuropathies. We recently showed that a subgroup of patients with aggressi...

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Bibliographic Details
Main Authors: Labasque, Marilyne, Hivert, Bruno, Nogales-Gadea, Gisela, Querol, Luis, Illa, Isabel, Faivre-Sarrailh, Catherine
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953301/
https://ncbi.nlm.nih.gov/pubmed/24497634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528489
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