A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

Steroid receptors activate and repress genes. An important class of genes that they repress is controlled by the transcription factor AP-1. The activity of AP-1 is inhibited by the receptor, a mechanism exploited for the therapy of various forms of pathological hyperproliferation in humans. We show...

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Main Authors: Heck, S, Kullmann, M, Gast, A, Ponta, H, Rahmsdorf, H J, Herrlich, P, Cato, A C
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC395330/
https://ncbi.nlm.nih.gov/pubmed/8076604
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