A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
Steroid receptors activate and repress genes. An important class of genes that they repress is controlled by the transcription factor AP-1. The activity of AP-1 is inhibited by the receptor, a mechanism exploited for the therapy of various forms of pathological hyperproliferation in humans. We show...
Uloženo v:
| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
1994
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8076604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06726.x |
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