Metabolic Reprogramming of Macrophages: GLUCOSE TRANSPORTER 1 (GLUT1)-MEDIATED GLUCOSE METABOLISM DRIVES A PROINFLAMMATORY PHENOTYPE

Glucose is a critical component in the proinflammatory response of macrophages (MΦs). However, the contribution of glucose transporters (GLUTs) and the mechanisms regulating subsequent glucose metabolism in the inflammatory response are not well understood. Because MΦs contribute to obesity-induced...

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Hlavní autoři: Freemerman, Alex J., Johnson, Amy R., Sacks, Gina N., Milner, J. Justin, Kirk, Erin L., Troester, Melissa A., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, Rathmell, Jeffery C., Makowski, Liza
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953299/
https://ncbi.nlm.nih.gov/pubmed/24492615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522037
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