Metabolic Reprogramming of Macrophages: GLUCOSE TRANSPORTER 1 (GLUT1)-MEDIATED GLUCOSE METABOLISM DRIVES A PROINFLAMMATORY PHENOTYPE

Glucose is a critical component in the proinflammatory response of macrophages (MΦs). However, the contribution of glucose transporters (GLUTs) and the mechanisms regulating subsequent glucose metabolism in the inflammatory response are not well understood. Because MΦs contribute to obesity-induced...

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Autors principals: Freemerman, Alex J., Johnson, Amy R., Sacks, Gina N., Milner, J. Justin, Kirk, Erin L., Troester, Melissa A., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, Rathmell, Jeffery C., Makowski, Liza
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953299/
https://ncbi.nlm.nih.gov/pubmed/24492615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522037
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