Metabolic Reprogramming of Macrophages: GLUCOSE TRANSPORTER 1 (GLUT1)-MEDIATED GLUCOSE METABOLISM DRIVES A PROINFLAMMATORY PHENOTYPE

Glucose is a critical component in the proinflammatory response of macrophages (MΦs). However, the contribution of glucose transporters (GLUTs) and the mechanisms regulating subsequent glucose metabolism in the inflammatory response are not well understood. Because MΦs contribute to obesity-induced...

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Detalhes bibliográficos
Main Authors: Freemerman, Alex J., Johnson, Amy R., Sacks, Gina N., Milner, J. Justin, Kirk, Erin L., Troester, Melissa A., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, Rathmell, Jeffery C., Makowski, Liza
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953299/
https://ncbi.nlm.nih.gov/pubmed/24492615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522037
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