Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

The product of the c-myc proto-oncogene, c-Myc, is a sequence-specific DNA binding protein with an N-terminal transactivation domain and a C-terminal DNA binding domain. Several lines of evidence indicate that c-Myc activity is essential for normal cell cycle progression. Since the abundance of c-My...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Beijersbergen, R L, Hijmans, E M, Zhu, L, Bernards, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8076603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06725.x
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