A Soluble Form of the Giant Cadherin Fat1 Is Released from Pancreatic Cancer Cells by ADAM10 Mediated Ectodomain Shedding

In pancreatic cancer, there is a clear unmet need to identify new serum markers for either early diagnosis, therapeutic stratification or patient monitoring. Proteomic analysis of tumor cell secretomes is a promising approach to indicate proteins released from tumor cells in vitro. Ectodomain sheddi...

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Autori principali: Wojtalewicz, Nathalie, Sadeqzadeh, Elham, Weiß, Jakob V., Tehrani, Mahnaz Moradian, Klein-Scory, Susanne, Hahn, Stephan, Schmiegel, Wolff, Warnken, Uwe, Schnölzer, Martina, de Bock, Charles E., Thorne, Rick F., Schwarte-Waldhoff, Irmgard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953070/
https://ncbi.nlm.nih.gov/pubmed/24625754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090461
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