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ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion

Trophoblasts, placental cells of epithelial lineage, undergo extensive differentiation to form the cellular components of the placenta. Trophoblast progenitor cell differentiation into the multinucleated syncytiotrophoblast is a key developmental process required for placental function, where defect...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Aghababaei, M, Hogg, K, Perdu, S, Robinson, W P, Beristain, A G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816105/
https://ncbi.nlm.nih.gov/pubmed/25909890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.44
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