Influence of In Vitro and In Vivo Oxygen Modulation on β Cell Differentiation From Human Embryonic Stem Cells

The possibility of using human embryonic stem (hES) cell-derived β cells as an alternative to cadaveric islets for the treatment of type 1 diabetes is now widely acknowledged. However, current differentiation methods consistently fail to generate meaningful numbers of mature, functional β cells. In...

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Detalhes bibliográficos
Main Authors: Cechin, Sirlene, Álvarez-Cubela, Silvia, Giraldo, Jaime A., Molano, Ruth D., Villate, Susana, Ricordi, Camillo, Pileggi, Antonello, Inverardi, Luca, Fraker, Christopher A., Domínguez-Bendala, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952934/
https://ncbi.nlm.nih.gov/pubmed/24375542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0160
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