A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner.

p47v-crk (v-Crk), a transforming gene product containing Src homology (SH)-2 and -3 domains, induces an elevated level of tyrosine phosphorylation of several cellular proteins. Among these proteins, a 125-135 kDa protein (p130) shows marked phosphorylation at tyrosines and tight association with v-C...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Sakai, R, Iwamatsu, A, Hirano, N, Ogawa, S, Tanaka, T, Mano, H, Yazaki, Y, Hirai, H
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8070403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06684.x
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