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An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

High-density lipoprotein (HDL) is believed to play an important role in lowering cardiovascular disease (CVD) risk by mediating the process of reverse cholesterol transport (RCT). Via RCT, excess cholesterol from peripheral tissues is carried back to the liver and hence should lead to the reduction...

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Detalhes bibliográficos
Main Authors: Lu, James, Hübner, Katrin, Nanjee, M. Nazeem, Brinton, Eliot A., Mazer, Norman A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952822/
https://ncbi.nlm.nih.gov/pubmed/24625468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003509
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