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An in-silico model of lipoprotein metabolism and kinetics for the evaluation of targets and biomarkers in the reverse cholesterol transport pathway.

High-density lipoprotein (HDL) is believed to play an important role in lowering cardiovascular disease (CVD) risk by mediating the process of reverse cholesterol transport (RCT). Via RCT, excess cholesterol from peripheral tissues is carried back to the liver and hence should lead to the reduction...

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Bibliografske podrobnosti
Main Authors: James Lu, Katrin Hübner, M Nazeem Nanjee, Eliot A Brinton, Norman A Mazer
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2014-03-01
Serija:PLoS Computational Biology
Online dostop:http://europepmc.org/articles/PMC3952822?pdf=render
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