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The ryanodine receptor agonist 4-chloro-3-ethylphenol blocks ORAI store-operated channels
BACKGROUND: Depletion of the Ca(2+) store by ryanodine receptor (RyR) agonists induces store-operated Ca(2+) entry (SOCE). 4-Chloro-3-ethylphenol (4-CEP) and 4-chloro-m-cresol (4-CmC) are RyR agonists commonly used as research tools and diagnostic reagents for malignant hyperthermia. Here, we invest...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952802/ https://ncbi.nlm.nih.gov/pubmed/24670147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12528 |
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