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Molecular biology of bcr-abl1–positive chronic myeloid leukemia

Chronic myeloid leukemia (CML) has been regarded as the paradigmatic example of a malignancy defined by a unique molecular event, the BCR-ABL1 oncogene. Decades of research zeroing in on the role of BCR-ABL1 kinase in the pathogenesis of CML have culminated in the development of highly efficacious t...

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Detalhes bibliográficos
Main Authors: Quintás-Cardama, Alfonso, Cortes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952549/
https://ncbi.nlm.nih.gov/pubmed/18827185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-144790
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