EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

Epstein-Barr virus (EBV) is unusual among DNA tumour viruses in that the virus particle is able to infect and immortalize resting cells with very high efficiency. Mutation of the viral genome has indicated that at least six viral genes (LMP-1 and EBNAs 1, 2, 3A, 3C and LP) are essential for immortal...

Full description

Bibliographic Details

Published in:	EMBO J
Main Authors:	Sinclair, A J, Palmero, I, Peters, G, Farrell, P J
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8045261/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06634.x
Tags:	Add Tag No Tags, Be the first to tag this record!