EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

Epstein-Barr virus (EBV) is unusual among DNA tumour viruses in that the virus particle is able to infect and immortalize resting cells with very high efficiency. Mutation of the viral genome has indicated that at least six viral genes (LMP-1 and EBNAs 1, 2, 3A, 3C and LP) are essential for immortal...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Sinclair, A J, Palmero, I, Peters, G, Farrell, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8045261/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06634.x
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