Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei

Cre-responsive dual-fluorescent alleles allow in situ marking of cell lineages or genetically modified cells. Here we report a dual-fluorescent allele, ROSA(nT-nG), that directs nuclear accumulation of tdTomato in Cre-naïve lineages. Cre converts the allele to ROSA(nG), which drives nuclear EGFP acc...

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Bibliografiske detaljer
Main Authors: Prigge, Justin R., Wiley, James A., Talago, Emily A., Young, Elise M., Johns, Laura L., Kundert, Jean A., Sonsteng, Katherine M., Halford, William P., Capecchi, Mario R., Schmidt, Edward E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952041/
https://ncbi.nlm.nih.gov/pubmed/24022199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-013-9469-8
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