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Humanized monoclonal antibody 2C9-cIgG has enhanced efficacy for yellow fever prophylaxis and therapy in an immunocompetent animal model

Yellow fever virus (YFV) causes significant human disease and mortality in tropical regions of South and Central America and Africa, despite the availability of an effective vaccine. No specific therapy for YF is available. We previously showed that the humanized monoclonal antibody (MAb) 2C9-cIgG p...

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Detalhes bibliográficos
Main Authors: Julander, Justin G., Thibodeaux, Brett A., Morrey, John D., Roehrig, John T., Blair, Carol D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951967/
https://ncbi.nlm.nih.gov/pubmed/24393669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.12.011
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