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A humanized IgG but not IgM antibody is effective in prophylaxis and therapy of yellow fever infection in an AG129/17D-204 peripheral challenge mouse model

Yellow fever virus (YFV), a member of the genus Flavivirus, is a mosquito-borne virus found in tropical regions of Africa and South America that causes severe hepatic disease and death in humans. Despite the availability of effective vaccines, YFV is responsible for an estimated 200,000 cases and 30...

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Библиографические подробности
Главные авторы: Thibodeaux, Brett A., Garbino, Nina C., Liss, Nathan M., Piper, Joseph, Schlesinger, Jacob J., Blair, Carol D., Roehrig, John T.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331901/
https://ncbi.nlm.nih.gov/pubmed/22366350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.02.001
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