A humanized IgG but not IgM antibody is effective in prophylaxis and therapy of yellow fever infection in an AG129/17D-204 peripheral challenge mouse model

Yellow fever virus (YFV), a member of the genus Flavivirus, is a mosquito-borne virus found in tropical regions of Africa and South America that causes severe hepatic disease and death in humans. Despite the availability of effective vaccines, YFV is responsible for an estimated 200,000 cases and 30...

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Hauptverfasser: Thibodeaux, Brett A., Garbino, Nina C., Liss, Nathan M., Piper, Joseph, Schlesinger, Jacob J., Blair, Carol D., Roehrig, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331901/
https://ncbi.nlm.nih.gov/pubmed/22366350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.02.001
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