A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment.

Insulin drives the formation of a complex between tyrosine-phosphorylated IRS-1 and SH2-containing proteins. The SH2-containing protein Grb2 also possesses adjacent SH3 domains, which bind the Ras guanine nucleotide exchange factor Sos. In this report, we examined the involvement of another SH3 bind...

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Autors principals: Ando, A, Yonezawa, K, Gout, I, Nakata, T, Ueda, H, Hara, K, Kitamura, Y, Noda, Y, Takenawa, T, Hirokawa, N
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC395193/
https://ncbi.nlm.nih.gov/pubmed/8039498
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