Human Degenerative Valve Disease Is Associated With Up-Regulation of Low-Density Lipoprotein Receptor-Related Protein 5 Receptor-Mediated Bone Formation

OBJECTIVES: The goal of this research was to define the cellular mechanisms involved in myxomatous mitral valve disease and calcific aortic valve disease and to redefine the term degenerative valve disease in terms of an active cellular biology. BACKGROUND: “Degenerative” valvular heart disease is t...

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Detalhes bibliográficos
Main Authors: Caira, Frank C., Stock, Stuart R., Gleason, Thomas G., McGee, Edwin C., Huang, Jie, Bonow, Robert O., Spelsberg, Thomas C., McCarthy, Patrick M., Rahimtoola, Shahbudin H., Rajamannan, Nalini M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951851/
https://ncbi.nlm.nih.gov/pubmed/16631011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2006.02.040
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