Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.

A soluble form of Alzheimer disease amyloid beta-protein (sA beta) is transported in the blood and cerebrospinal fluid mainly complexed with apolipoprotein J (apoJ). Using a well-characterized in situ perfused guinea pig brain model, we recently obtained preliminary evidence that apoJ facilitates tr...

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Bibliografiska uppgifter
Huvudupphovsmän: Zlokovic, B V, Martel, C L, Matsubara, E, McComb, J G, Zheng, G, McCluskey, R T, Frangione, B, Ghiso, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC39517/
https://ncbi.nlm.nih.gov/pubmed/8633046
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