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THE ROLE OF TUMOR PROGRESSION LOCUS 2 (TPL-2) PROTEIN KINASE IN GLIAL INFLAMMATORY RESPONSE

Tumor progression locus 2 (Tpl2)/Cot kinase is a newer member of MAP3K family that is now known for its essential role in TNFα expression in macrophages, but its proinflammatory signaling, if any, in glia is unknown. When cultures of murine microglia and astrocytes were exposed to lipopolysaccharide...

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Autors principals: Hirschhorn, Joshua, Mohanty, Sangeeta, Bhat, Narayan R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951670/
https://ncbi.nlm.nih.gov/pubmed/24188160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12522
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