Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.

We have recently cloned a novel cytokine, IL-15, with shared bioactivities but no sequence homology with IL-2. We found high affinity IL-15 binding to many cell types, including cells of non-lymphoid origin. Analysis of IL-15 interaction with subunits of the IL-2 receptor (IL-2R) revealed that the a...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Giri, J G, Ahdieh, M, Eisenman, J, Shanebeck, K, Grabstein, K, Kumaki, S, Namen, A, Park, L S, Cosman, D, Anderson, D
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8026467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06576.x
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