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Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.

We have recently cloned a novel cytokine, IL-15, with shared bioactivities but no sequence homology with IL-2. We found high affinity IL-15 binding to many cell types, including cells of non-lymphoid origin. Analysis of IL-15 interaction with subunits of the IL-2 receptor (IL-2R) revealed that the a...

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Sparad:
I publikationen:EMBO J
Huvudupphov: Giri, J G, Ahdieh, M, Eisenman, J, Shanebeck, K, Grabstein, K, Kumaki, S, Namen, A, Park, L S, Cosman, D, Anderson, D
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Publishing Group 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8026467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06576.x
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