Raloxifene and anti-estrogenic Gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem like cells

Studies suggest that estrogen plays a contributing role in colorectal cancer (CRC). This project examined the preventive effects of raloxifene, a selective estrogen receptor modulator (SERM), and gonadorelin, an anti-estrogenic drug, in female Apc(Min/+) mouse intestinal tumorigenesis. Six-week-old...

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Bibliographic Details
Main Authors: Janakiram, Naveena B., Mohammed, Altaf, Brewer, Misty, Bryant, Taylor, Biddick, Laura, Lightfoot, Stan, Pathuri, Gopal, Gali, Hariprasad, Rao, Chinthalapally V.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951612/
https://ncbi.nlm.nih.gov/pubmed/24431404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0345
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