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A key regulatory role of Vav1 in controlling LPS endotoxemia via macrophage derived IL-6
Macrophages are centrally involved in the pathogenesis of acute inflammatory diseases, peritonitis, endotoxemia and septic shock. The molecular mechanisms controlling such macrophage activation are incompletely understood, however. Here, we provide evidence that Vav1, a member of the RhoGEF family,...
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Päätekijät: | , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2014
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951479/ https://ncbi.nlm.nih.gov/pubmed/24532586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300157 |
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