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Function of the Nucleotide Exchange Activity of Vav1 in T cell Development and Activation()
The guanine nucleotide exchange factor (GEF) Vav1 is essential for transducing T cell antigen receptor (TCR) signals and therefore plays a critical role in the development and activation of T cells. It has been presumed that the GEF activity of Vav1 is important for its function; however, there has...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434450/ https://ncbi.nlm.nih.gov/pubmed/20009105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000420 |
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