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MicroRNA-608 and MicroRNA-34a Regulate Chordoma Malignancy by Targeting EGFR, Bcl-xL and MET

Chordomas are rare malignant tumors that originate from the notochord remnants and occur in the skull base, spine and sacrum. Due to a very limited understanding of the molecular pathogenesis of chordoma, there are no adjuvant and molecular therapies besides surgical resection and radiation therapy....

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Hlavní autoři: Zhang, Ying, Schiff, David, Park, Deric, Abounader, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951453/
https://ncbi.nlm.nih.gov/pubmed/24621885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091546
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