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microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

We recently found that microRNA-34a (miR-34a) is downregulated in human glioma tumors as compared to normal brain, and that miR-34a levels in mutant-p53 gliomas were lower than in wildtype-p53 tumors. We showed that miR-34a expression in glioma and medulloblastoma cells inhibits cell proliferation,...

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Autori principali: Guessous, Fadila, Zhang, Ying, Kofman, Alexander, Catania, Alessia, Li, Yunqing, Schiff, David, Purow, Benjamin, Abounader, Roger
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278213/
https://ncbi.nlm.nih.gov/pubmed/20190569
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