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Synthesis of C11-Desmethoxy Soraphen A(1α): A Natural Product Analogue That Inhibits Acetyl-CoA Carboxylase

[Image: see text] A synthesis of C11-desmethoxy soraphen A(1α) is described that proceeds in just 14 steps from readily available starting materials. This natural product analogue was identified as a target of interest in a program aimed at identifying novel natural product-inspired inhibitors of ac...

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Detalhes bibliográficos
Main Authors: Canterbury, Daniel P., Scott, Kristen E. N., Kubo, Ozora, Jansen, Rolf, Cleveland, John L., Micalizio, Glenn C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951358/
https://ncbi.nlm.nih.gov/pubmed/24639892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400377p
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