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Potent induction of antibody-secreting B-cells by human dermal-derived CD14(+) dendritic cells triggered by dual Toll-like receptor ligation
Targeting CD14(+) dermal-derived dendritic cells (DDCs) is a rational approach for vaccination strategies aimed at improving humoral immune responses, because of their natural ability to stimulate naïve B-cells. Here, we show that CD14(+) DDCs express mRNA for TLRs 1–9, but respond differentially to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951118/ https://ncbi.nlm.nih.gov/pubmed/23162132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200601 |
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